RNA-Seq data of terminal differentiated cells in Dictyostelium discoideum
Ontology highlight
ABSTRACT:
INSTRUMENT(S): NextSeq 500
ORGANISM(S): Dictyostelium discoideum
SUBMITTER: Pauline Schaap
PROVIDER: E-MTAB-7215 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Cell-type specific RNA-Seq reveals novel roles and regulatory programs for terminally differentiated Dictyostelium cells.
Kin Koryu K Forbes Gillian G Cassidy Andrew A Schaap Pauline P
BMC genomics 20181022 1
<h4>Background</h4>A major hallmark of multicellular evolution is increasing complexity by the evolution of new specialized cell types. During Dictyostelid evolution novel specialization occurred within taxon group 4. We here aim to retrace the nature and ancestry of the novel "cup" cells by comparing their transcriptome to that of other cell types.<h4>Results</h4>RNA-Seq was performed on purified mature spore, stalk and cup cells and on vegetative amoebas. Clustering and phylogenetic analyses s ...[more]
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