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Pancreatic Cancer miRNA expression profiles

ABSTRACT:

ORGANISM(S): Homo sapiens

DISEASE(S): Normal

SUBMITTER: Massimo Carella

PROVIDER: E-MTAB-753 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Mirna expression profiles identify drivers in colorectal and pancreatic cancers.

Piepoli Ada A Tavano Francesca F Copetti Massimiliano M Mazza Tommaso T Palumbo Orazio O Panza Anna A di Mola Francesco Fabio FF Pazienza Valerio V Mazzoccoli Gianluigi G Biscaglia Giuseppe G Gentile Annamaria A Mastrodonato Nicola N Carella Massimo M Pellegrini Fabio F di Sebastiano Pierluigi P Andriulli Angelo A

PloS one 20120330 3

<h4>Background and aim</h4>Altered expression of microRNAs (miRNAs) hallmarks many cancer types. The study of the associations of miRNA expression profile and cancer phenotype could help identify the links between deregulation of miRNA expression and oncogenic pathways.<h4>Methods</h4>Expression profiling of 866 human miRNAs in 19 colorectal and 17 pancreatic cancers and in matched adjacent normal tissues was investigated. Classical paired t-test and random forest analyses were applied to identi ...[more]

PMID: 22479426

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