Ontology highlight
ABSTRACT:
INSTRUMENT(S): NextSeq 500
ORGANISM(S): Homo sapiens
SUBMITTER: Fabio Luciani
PROVIDER: E-MTAB-7606 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Nature immunology 20190218 5
Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally and infect humans, with IAV and IBV causing the most severe disease. CD8<sup>+</sup> T cells confer cross-protection against IAV strains, however the responses of CD8<sup>+</sup> T cells to IBV and ICV are understudied. We investigated the breadth of CD8<sup>+</sup> T cell cross-recognition and provide evidence of CD8<sup>+</sup> T cell cross-reactivity across IAV, IBV and ICV. We identified immunodominant CD8<sup>+ ...[more]