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Gene expression analysis of 789 cancer cell lines using the Affymetrix HT- HG-U133A v2 platform.

ABSTRACT: RNA extracted from each cell line was hybridised to the array.

ORGANISM(S): Homo sapiens

SUBMITTER: Ultan McDermott

PROVIDER: E-MTAB-783 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Comparison and validation of genomic predictors for anticancer drug sensitivity.

Papillon-Cavanagh Simon S De Jay Nicolas N Hachem Nehme N Olsen Catharina C Bontempi Gianluca G Aerts Hugo J W L HJ Quackenbush John J Haibe-Kains Benjamin B

Journal of the American Medical Informatics Association : JAMIA 20130126 4

<h4>Background</h4>An enduring challenge in personalized medicine lies in selecting the right drug for each individual patient. While testing of drugs on patients in large trials is the only way to assess their clinical efficacy and toxicity, we dramatically lack resources to test the hundreds of drugs currently under development. Therefore the use of preclinical model systems has been intensively investigated as this approach enables response to hundreds of drugs to be tested in multiple cell l ...[more]

PMID: 23355484

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