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Affymetrix HG-U133A gene expression profiles of 39 human breast cancer cell lines

ABSTRACT: Microarrays were used to detail the global programme of gene expression underlying breast cancer cell lines. We identified two main groups of luminal-type and basal-type breast cancer cell lines by unsupervised Pearson correlation of breast cancer cell lines and intrinsic subtyping. Supervised analysis on spindle versus non-spindle breast cancer cell lines identified a spindle cell signature of 1,144 genes identifying all spindle, basal-type, E-cadherin methylated breast cancer cell lines. Breast cancer cell lines were grown to optimal cell densities for RNA extraction and hybridization on Affymetrix microarrays.

ORGANISM(S): Homo sapiens

SUBMITTER: Hollestelle A

PROVIDER: S-ECPF-GEOD-16795 | biostudies-other | 2010 May

REPOSITORIES: biostudies-other

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Affymetrix HG-U133A gene expression profiles of 39 human breast cancer cell lines

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