Transcription profiling of Listeria monocytogenes wild type and cadC deletion mutant grown in BHI at 37ºC

ABSTRACT: CadC is the transcriptional regulator of CadA, an efflux pump conferring cadmium resistance. We previously showed that during in vivo infection, Listeria monocytogenes uses CadC to directly repress the expression of the LspB lipoprotein signal peptidase, avoiding the exposure of the lipoprotein LpeA to the host immune system, impairing inflammatory cytokine expression and promoting intramacrophage survival and virulence. Here, to assess if CadC could be a widespread virulence regulator, we searched for other genes regulated by CadC using Listeria monocytogenes tiling arrays.

ORGANISM(S): Listeria monocytogenes EGD-e

SUBMITTER: Didier Cabanes 

PROVIDER: E-MTAB-7857 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress