Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

22 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Microarray of porcine samples after repairing using tissue engineering graft

ABSTRACT: After implantion into porcine condyles at knee, the samples were harvested and the RNA was attracted, the RNA harvested was compared to all native surrounding tissues to study the phenotype of the regenerated cartilaginous tissue.

ORGANISM(S): Sus scrofa

SUBMITTER: Xiaolei NIE

PROVIDER: E-MTAB-7986 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Osteoblast primary cell lines (OBS) from Shwachman-Diamond Syndrome (SDS) patients compared to healthy donors by one color transciptome array

Project description:The idea was to evaluate the transcriptome differences between osteoblasts derived from SDS patients compared to healthy donors and especially to enlighten the bone-related genes deregulation. The aim was to identify genes involved in SDS-related bone defects.

2020-08-15 | E-MTAB-9397 | biostudies-arrayexpress

The comparison of exosomal miRNAs from ECM or media derived from HFF-CBD-Lamp2b cells, HFF cells, HFF-Lamp2b cells and hUCMSCs

Project description:The next-generation sequencing technology was used to investigate the difference of RNAs content among the different types of exosomes from the media of HFF cells, HFF-Lamp2b cells and hUCMSCs, and from the ECM of HFF-CBD-Lamp2b cells

2021-10-12 | E-MTAB-10905 | biostudies-arrayexpress

Gene expression analysis of CD11c+ splenic DCs day 7 after allo-HSCT.

Project description:The goal of our study is to determine whether Atg16L1 deficiency leads to differences in the transcriptional profile of CD11c+ Dendritic Cells, ultimately leading to an increased inflammatory phenotype. CD11c+ cell sorted splenic DCs were isolated from 8 week old WT and Atg16L1 hypomorphic mice from spleens of allo-HSCT recipients on day 7 were placed directly into TRIzol LS (Invitrogen). mRNA was isolated, amplified, and hybridized to an Affymetrix GeneChip (MOE430A).

2014-09-19 | E-GEOD-61560 | biostudies-arrayexpress

The RNA-seq of knee joint cartilaginous tissues of conditionally knockout Hbb or wildtype postnatal day 6 mice

Project description:To investigate the gene expression difference between knee joint cartilaginous tissues of conditionally knockout Hbb or wildtype postnatal day 6 mice.

2021-09-30 | GSE182640 | GEO

Transcriptomic signatures of cartilage ageing

Project description:Equine cartilage from young and old donors was used for RNA-Seq analysis. The aim of the study was to identify differentially expressed cartilage transcripts in ageing in order to to characterize molecular mechanisms associated with age-related changes in

2014-01-11 | E-MTAB-1386 | biostudies-arrayexpress

Novel Targets of the Transcription Factor Sox9 in Neonatal Mouse Limb

Project description:Sox9 is an SRY-related transcription factor required for expression of cartilaginous matrix genes in the developing skeletal system and heart valve structures. In contrast to positively regulating formation of cartilaginous matrix, Sox9 has also been shown to negatively regulate matrix mineralization associated with bone formation. While the transcriptional activation of Sox9 target genes during chondrogenesis has been well studied, the mechanisms by which Sox9 represses osteogenic processs are not so clear. To address this, we performed a genome-wide Sox9 ChIP-on-chip approach using neonatal mouse lim tissue. Chromatin immunoprecipitation was performed with pooled Sox9 antibodies and normal rabbit IgG as control using neonatal mouse limb tissue. Samples include Sox9 IP and IgG IP.

2011-11-01 | E-GEOD-29058 | biostudies-arrayexpress

CD11c+ splenic DCs

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-09-19 | E-GEOD-61561 | biostudies-arrayexpress

Transcription profiling of human PBMC from autoimmune ear disease (AIED) patients to assess IL1R2 and glucocorticoid response

Project description:Glucocorticoid responsive AIED patients demonstrate alternate splicing of IL1R2 in response to dexamethasone prior to treatment. Identification of IL1R2 as a potential target gene in AIED was determined by a microarray analysis of patients with end-stage AIED and controls with non-immunologic etiologies of hearing loss undergoing cochlear implantation. Experiment Overall Design: Patients with either end-stage AIED or controls with non-immunologic etiologies of hearing loss undergoing cochlear implantation were enrolled. All patients received pneumovax 2 weeks prior to surgery. At the time of surgery, blood was taken for PBMC isolation and autologous perilymph was harvested from a bloodless field. For each patient, 3 microarrays were performed: (1) unstimulated PBMC, (2) pneumovax stimulated PBMC, (3) autologous perilymph stimulated PBMC. All conditions were compared for the AIED and control subjects. IL1R2 was identified as induced in controls, but not AIED patients, in response to autologous perilymph. Findings were confirmed by QPCR.

2009-05-11 | E-GEOD-4277 | biostudies-arrayexpress

Novel Targets of the Transcription Factor Sox9 in Neonatal Mouse Limb

2011-11-01 | GSE29058 | GEO

BMP4 promotes development and patterning of the tracheal cartilage and trachealis muscle downstream of epithelial-induced Wnt signaling

Project description:By differentially regulating expression of direct Wnt/b-catenin target genes, Bmp4 modulates levels of Wnt signaling necessary to promote cartilaginous identity and progress tracheal chondrogenesis.

2021-10-01 | GSE158452 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data