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RNAseq of pancreata from KRasG12D/RosaMycER treated with Tamoxifen for different times

ABSTRACT: Experiment designed to study the effect of deregulated myc on pancreatic cancer progression and regression. In the KRasG12D/RosaMycER mouse model KRas and MycER are expressed exclusively in the pancreas, but MycER activity depends on Tamoxifen presence. RNAseq was preformed on pancreata from mice treated with Tamoxifen as follows: 1- Normal food. 2- Tamoxifen food 2 weeks. 3- Tamoxifen food 2 weeks, followed by normal food 1 day. 4- Tamoxifen food 2 weeks, followed by normal food 3 days.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Mus musculus

SUBMITTER: Tania Campos

PROVIDER: E-MTAB-8467 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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RNAseq of pancreatas from KRasG12D/RosaMycER treated with Tamoxifen for different times. MycOFF short times.

Project description:Experiment designed to study the effect of deregulated myc on pancreatic cancer progression and regression. In the KRasG12D/RosaMycER mouse model KRas and MycER are expressed exclusively in the pancreas, but MycER activity depends on Tamoxifen presence. RNAseq was preformed on pancreatas from mice treated with Tamoxifen as follows: 1-Tamoxifen food 2 weeks. 2- Tamoxifen food 2 weeks, followed by normal food 6 hours day. 3- Tamoxifen food 2 weeks, followed by normal food 12 hours.

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RNAseq of pancreata from KRasG12D/RosaMycER treated with Tamoxifen for different times

Project description:RNAseq of pancreata from KRasG12D/RosaMycER treated with Tamoxifen for different times

| PRJEB35067 | ENA

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