Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Mus musculus
SUBMITTER: Benjamin Simons
PROVIDER: E-MTAB-8656 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Yum Min Kyu MK Han Seungmin S Fink Juergen J Wu Szu-Hsien Sam SS Dabrowska Catherine C Trendafilova Teodora T Mustata Roxana R Chatzeli Lemonia L Azzarelli Roberta R Pshenichnaya Irina I Lee Eunmin E England Frances F Kim Jong Kyoung JK Stange Daniel E DE Philpott Anna A Lee Joo-Hyeon JH Koo Bon-Kyoung BK Simons Benjamin D BD
Nature 20210602 7863
Interactions between tumour cells and the surrounding microenvironment contribute to tumour progression, metastasis and recurrence<sup>1-3</sup>. Although mosaic analyses in Drosophila have advanced our understanding of such interactions<sup>4,5</sup>, it has been difficult to engineer parallel approaches in vertebrates. Here we present an oncogene-associated, multicolour reporter mouse model-the Red2Onco system-that allows differential tracing of mutant and wild-type cells in the same tissue. B ...[more]