Ontology highlight
ABSTRACT:
ORGANISM(S): Streptomyces coelicolor
SUBMITTER: Ales Ulrych
PROVIDER: E-MTAB-894 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Ulrych Aleš A Goldová Jana J Petříček Miroslav M Benada Oldřich O Kofroňová Olga O Rampírová Petra P Petříčková Kateřina K Petříčková Kateřina K Branny Pavel P
Molecular bioSystems 20130326 6
The genome of Streptomyces coelicolor encodes six potential WD-40 genes. Two of them, the wdpB (SCO5953) and the wdpC (SCO4422) genes, were studied to determine their function. Deletion of the wdpB gene resulted in a considerable decrease of aerial hyphae formation, leading to a conditionally bald phenotype, and reduced undecylprodigiosin production. In addition, the aerial hyphae of the ΔwdpB mutant strain were unusually branched and showed the signs of irregular septation and precocious lysis. ...[more]