Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq of DCIS-pInducer21-SOX11 cells grown in 2D and 3D


ABSTRACT: Using the pINDUCER21 system, we modified DCIS.com cells so that SOX11 is expressed at much higher levels after induction with Doxycycline (Dox) than observed with the constitutive DCIS-SOX11 cells we have used to model DCIS progression. After Dox induction of pIND21-SOX11 cells, both SOX11 and CD24 expression are significantly increased ). Higher ALDH levels are detected in pIND21-SOX11 cells, suggesting that high levels of SOX11 promotes acquisition of features associated with distinct types of cancer stem cells.

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Homo sapiens

SUBMITTER: Erik Oliemuller 

PROVIDER: E-MTAB-9108 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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