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Unknown,Transcriptomics,Genomics,Proteomics

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Promoter Capture-C of iPSC-derived NPCs and neurons

ABSTRACT: To connect the neuronal developmental disorders associated GWAS signal to their target effector genes, we performed an integrated analysis of transcriptomics, epigenomics and chromatin conformation changes in an in vitro cellular model. Induced human pluripotent stem cell–derived neural progenitor cells (NPCs) were differentiated into neurons and then subjected to a combination of high-resolution promoter-focused Capture C, ATAC-seq and RNA-seq.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Chun Su

PROVIDER: E-MTAB-9159 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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