Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptome Profiling of Human Monocyte-Derived Macrophages Upon CCL2 Neutralization Reveals an Association Between Activation of Innate Immune Pathways and Restriction of HIV-1


ABSTRACT: We used RNA-sequencing to deeply characterize the cellular factors and pathways modulated by CCL2 blocking in MDMs and involved in HIV-1 replication restriction. Gene differential expression analysis was performed and then Functional annotation was done to up-regulated genes Reads that failed mapping to human genome was mapped to HIV-1 reference genome. Note that some samples in this experiment have no raw files as the data has been lost.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Homo sapiens

SUBMITTER: Jing Lu 

PROVIDER: E-MTAB-9414 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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