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Unknown,Transcriptomics,Genomics,Proteomics

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The transcriptome-wide CPSF6-induced APA alterations in HCC cells

ABSTRACT: In this study, we showed that CPSF6 promoted HCC cell growth, migration and metastasis in vitro and in vivo. In order to understand the underlying mechanisms of CPSF6, we aimed to perform a APA profiling analysis in hepatocyte and hepatoma carcinoma cells under different CPSF6 expression conditions using 3T-seq method.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Homo sapiens

SUBMITTER: Tan Sheng

PROVIDER: E-MTAB-9458 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The transcriptome-wide CPSF6-induced APA alterations in gastric cancer cells

Project description:In this study, we showed that knockdown of CPSF6 inhibited GC cell growth and promoted apoptosis in vitro and in vivo. In order to understand the underlying mechanisms of CPSF6, we performed an APA profiling analysis in wild-type and CPSF6-knockdown AGS cells, using 3T-seq method.

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Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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