RNA-Seq analysis of E18.5 mouse Zfp800 knockout vs wild-type
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ABSTRACT: Zfp800 was identified by Gene Co-expression Network analysis to be an interesting candidate gene involved in endocrine specification and β-cell maturation. We found that Zfp800 null mice exhibited early post-natal lethality, and at E18.5 their pancreata exhibited a reduced number of pancreatic endocrine cells, alterations in exocrine cell morphology, and marked changes in genes involved in protein translation, hormone secretion, and developmental pathways in the pancreas.
INSTRUMENT(S): Illumina NovaSeq 6000
ORGANISM(S): Mus musculus
SUBMITTER: Mark Magnuson
PROVIDER: E-MTAB-9538 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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