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Gene expression profiling by array of human non-transformed RPE-FUCCI (Fluorescent Ubiquitination-based Cell Cycle Indicator) cells

ABSTRACT: Progression through the cell cycle is driven by cyclin dependent kinases that control gene expression, orchestration of the mitotic spindle and cell division. Here we used a Fluorescent Ubiquitination-based Cell Cycle Indicator (FUCCI) and performed transcriptomic analysis of human non-transformed cells. Cell sorting allowed efficient isolation of G1, S and G2 cells from asynchronously growing cell cultures. Altogether, we identified 701 differentially expressed genes in G1 and G2 cells.

ORGANISM(S): Homo sapiens

SUBMITTER: Cecilia Aquino Perez

PROVIDER: E-MTAB-9626 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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