Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of human invasive breast cancer carcinomas with different histological types and invasive lobular carcinoma


ABSTRACT: Gene expression array analysis on a series of ten different histological special types of invasive breast carcinomas (tubular, micropapillary, mucinous A, mucinous B, endocrine, apocrine, metaplastic, medullary, adenoid cystic, invasive ductal carcinoma with osteoclastic giant cells) and invasive lobular carcinoma.

Note: this experiment was reloaded into ArrayExpress in August 2010 to include mappings between raw and processed data files. It now includes additional dye-swap combined normalized data files.

ORGANISM(S): Homo sapiens

SUBMITTER: Cor Lieftink 

PROVIDER: E-NCMF-3 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Transcriptomic analysis of tubular carcinomas of the breast reveals similarities and differences with molecular subtype-matched ductal and lobular carcinomas.

Lopez-Garcia Maria A MA   Geyer Felipe C FC   Natrajan Rachael R   Kreike Bas B   Mackay Alan A   Grigoriadis Anita A   Reis-Filho Jorge S JS   Weigelt Britta B  

The Journal of pathology 20100901 1


Tubular carcinoma (TC) is an uncommon special type of breast cancer characterized by an indolent clinical course. Although described as part of a spectrum of related lesions named 'low-grade breast neoplasia family' due to immunophenotypical and genetic similarities, TCs, low-grade invasive ductal carcinomas of no special type (IDC-NSTs), and classic invasive lobular carcinomas (ILCs) significantly differ in terms of histological features and clinical outcome. The aim of this study was to invest  ...[more]

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