Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): normal
SUBMITTER: Anita Grigoriadis
PROVIDER: E-TABM-10 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Clinical cancer research : an official journal of the American Association for Cancer Research 20061201 24
<h4>Purpose</h4>The most well established molecular markers of poor outcome in Wilms' tumor are loss of heterozygosity at chromosomes 1p and/or 16q, although to date no specific genes at these loci have been identified. We have previously shown a link between genomic gain of chromosome 1q and tumor relapse and sought to further elucidate the role of genes on 1q in treatment failure.<h4>Experimental design</h4>Microarray-based comparative genomic hybridization identified a microamplification harb ...[more]