Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

45 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MiRNAs expression data from Atm++ and Atm-- mouse embryonic fibroblasts after DNA damage at various time point

ABSTRACT: Atm++ and Atm-- mouse embryonic fibroblasts were treated with DNA damaging agent neocarzinostatin (NCS), and cells were harvested at indicated time points for the microarray analyses of whole-genome miRNAs. To examine how miRNAs are regulated in the DNA damage response, we assessed the genome-wide mature miRNA expression in Atm++ and Atm-- littermate mouse embryonic fibroblasts (MEFs).

ORGANISM(S): Mus musculus

SUBMITTER: Guohui Wan

PROVIDER: E-TABM-1092 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

MiRNAs expression data from Atm+/+ and Atm-/- mouse embryonic fibroblasts after DNA damage at various time point

Project description:Atm+/+ and Atm-/- mouse embryonic fibroblasts were treated with DNA damaging agent neocarzinostatin (NCS), and cells were harvested at indicated time points for the microarray analyses of whole-genome miRNAs. To examine how miRNAs are regulated in the DNA damage response, we assessed the genome-wide mature miRNA expression in Atm+/+ and Atm-/- littermate mouse embryonic fibroblasts (MEFs).

2010-12-09 | E-GEOD-25916 | biostudies-arrayexpress

MiRNAs expression data from GM0637 treated with and without ATM inhibitor after DNA damage

Project description:GM0637 cell were pretreated with ATM inhibitor before adding DNA damaging agent neocarzinostatin (NCS), and cells were harvested after 4 hours for the microarray analyses of whole-genome miRNAs. To examine how miRNAs are regulated in the DNA damage response, we assessed the genome-wide mature miRNA expression in GM0637 cells treated with or without ATM inhibitor (ATM-IN)

2012-11-14 | E-GEOD-42248 | biostudies-arrayexpress

Long noncoding RNAs expression data from Atm+/+ and Atm-/- mouse embryonic fibroblasts after DNA damage at various time point

Project description:Atm+/+ and Atm-/- mouse embryonic fibroblasts were treated with or without DNA damaging agent neocarzinostatin (NCS), and cells were harvested after 4 hours and 8 hours for the microarray analyses of whole-genome long noncoding RNAs. To examine how long noncoding RNAs are regulated in the DNA damage response, we assessed the genome-wide long noncoding RNA expression in Atm+/+ and Atm-/- littermate mouse embryonic fibroblasts (MEFs) treated with or without DNA damage

2013-01-17 | E-GEOD-43425 | biostudies-arrayexpress

long noncoding RNAs expression data from GM0637 with and without DNA damage

Project description:GM0637 cell were treated with or without DNA damaging agent neocarzinostatin (NCS), and cells were harvested after 4 hours and 8 hours for the microarray analyses of whole-genome long noncoding RNAs. To examine how long noncoding RNAs are regulated in the DNA damage response, we assessed the genome-wide long noncoding RNA expression in GM0637 cells treated with or without DNA damage

2013-01-17 | E-GEOD-43509 | biostudies-arrayexpress

MiRNAs expression data from Atm+/+ and Atm-/- mouse embryonic fibroblasts after DNA damage at various time point

2010-12-09 | GSE25916 | GEO

Long noncoding RNAs expression data from Atm+/+ and Atm-/- mouse embryonic fibroblasts after DNA damage at various time point

2013-01-17 | GSE43425 | GEO

MiRNAs expression data from GM0637 treated with and without ATM inhibitor after DNA damage

2012-11-14 | GSE42248 | GEO

EpCAM-Aptamer Toxin Conjugates for targeting tumors

Project description:Neocarzinostatin (NCS) is an anti-tumor DNA damaging agent. Conjugating NCS with EpCAM Aptamer will direct the toxin pay loads to the EpCAM positive cancer cells as a targeted therapy We used microarrays to detail the global gene expression to understand the pathways involved in EpCAM-mediated NCS drug delivery in breast cancer cells.

2018-09-05 | GSE69160 | GEO

RNAi knock down of ATM, p53 Rel_A subunit of NFkB or LacZ in human HEK293 cells treated with the radiomimetic drug NCS

Project description:Response to treatment with the radiomimetic drug NCS in cells knocked-down for ATM, p53, and the Rel_A subunit of NFkB; and in control un-infected cells and cells infected with siRNA against LacZ

2007-10-02 | E-GEOD-1676 | biostudies-arrayexpress

long noncoding RNAs expression data from GM0637 with and without DNA damage

2013-01-17 | GSE43509 | GEO