Dataset Information
Transcription profiling of matching human primary head and neck squamous cell carcinomas and cervical lymph node metastases.
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): oropharynx squamous-cell carcinoma in DiseaseLocation oropharynx has DiseaseStaging lymph node negative (N0)
SUBMITTER: Paul Roepman
PROVIDER: E-TABM-114 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Maintenance of head and neck tumor gene expression profiles upon lymph node metastasis.
Cancer research 20061201 23
Spread of cancer and development of solid metastases at distant sites is the main cause of cancer-related deaths. To understand and treat metastases, it is important to determine at which stages the most pivotal steps for development of metastases occur. In head and neck squamous cell carcinoma (HNSCC), metastasis nearly always occurs first in local lymph nodes before development of distant metastasis. Here, we have investigated gene expression patterns in HNSCC lymph node metastases using DNA m ...[more]
