Transcription profiling of yeast to determine mRNA stability at different time points following mild hyperosmotic shock
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Alexandra Jauhiainen
PROVIDER: E-TABM-622 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
mRNA stability changes precede changes in steady-state mRNA amounts during hyperosmotic stress.
Molin Claes C Jauhiainen Alexandra A Warringer Jonas J Nerman Olle O Sunnerhagen Per P
RNA (New York, N.Y.) 20090217 4
Under stress, cells need to optimize the activity of a wide range of gene products during the response phases: shock, adaptation, and recovery. This requires coordination of several levels of regulation, including turnover and translation efficiencies of mRNAs. Mitogen-activated protein (MAP) kinase pathways are implicated in many aspects of the environmental stress response, including initiation of transcription, translation efficiency, and mRNA turnover. In this study, we analyze mRNA turnover ...[more]
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