Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Juha Mykkänen
PROVIDER: E-TABM-666 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Journal of autoimmunity 20100330 1
Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing pancreatic beta cells in the islets of Langerhans. Although defects in various T cell subsets have been linked to the disease pathogenesis, mechanisms initiating or enhancing the autoimmunity in prediabetes remain poorly understood. To unravel genes and molecular pathways affected by the diabetes-associated autoimmunity, we investigated transcriptomic profiles of prospective whole-blood samples from children who have ...[more]