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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling by array of Arabidopsis wild type and RETINOBLASTOMA-RELATED (RBR) RNAi plants (early timepoints)

ABSTRACT: RNA was labeled and hybridized to ATH1 arrays.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Lars Hennig

PROVIDER: E-TABM-918 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Arabidopsis RETINOBLASTOMA-RELATED is required for stem cell maintenance, cell differentiation, and lateral organ production.

Borghi Lorenzo L Gutzat Ruben R Fütterer Johannes J Laizet Yec'han Y Hennig Lars L Gruissem Wilhelm W

The Plant cell 20100604 6

Several genes involved in the regulation of postembryonic organ initiation and growth have been identified. However, it remains largely unclear how developmental cues connect to the cell cycle. RETINOBLASTOMA RELATED (RBR) is a plant homolog of the tumor suppressor Retinoblastoma (pRb), which is a key regulator of the cell cycle. Using inducible RNA interference (RNAi) against Arabidopsis thaliana RBR (RBRi), we reduced RBR expression levels at different stages of plant development. Conditional ...[more]

PMID: 20525851

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