Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling by array of human Acute Myeloid Leukemia samples

ABSTRACT:

ORGANISM(S): Homo sapiens

DISEASE(S): Acute Myeloid Leukemia

SUBMITTER: Emanuele Marchi 

PROVIDER: E-TABM-978 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

The relationships between normal and leukemic stem/progenitor cells are unclear. We show that in ∼80% of primary human CD34+ acute myeloid leukemia (AML), two expanded populations with hemopoietic progenitor immunophenotype coexist in most patients. Both populations have leukemic stem cell (LSC) activity and are hierarchically ordered; one LSC population gives rise to the other. Global gene expression profiling shows the LSC populations are molecularly distinct and resemble normal progenitors bu  ...[more]

Similar Datasets

Transcriptomics Transcription profiling of diabetic vs non-diabetic human blood cells infected with Burkholderia pseudomallei
2010-12-31 | E-TABM-852 | biostudies-arrayexpress
Transcriptomics Transcription profiling of human blood cells in different times after vaccination with 1,2 or 3 doses of BCG
2010-12-31 | E-TABM-853 | biostudies-arrayexpress
Transcriptomics Transcription profiling of blood from HIV positive adults with non-typhoidal salmonellosis
2010-06-25 | E-TABM-856 | biostudies-arrayexpress
Transcriptomics miRNA profiling of human blood cells from patients with acute and chronic infection with the geohelminth ascaris lumbricoides
2012-08-31 | E-TABM-939 | biostudies-arrayexpress
Transcriptomics Transcription profiling of various cell types isolated from pancreatic islet grafts in Id1/Id3 deficient and wild type mice
2008-06-13 | E-TABM-355 | biostudies-arrayexpress
Transcriptomics Transcription profiling of mouse B lymphocytes after thapsigargin-stimulated ER stress for 8 and 24 hours to elucidate factors that influence T cell priming
2008-04-16 | E-TABM-240 | biostudies-arrayexpress
Transcriptomics Transcription profiling by array of human untreated endometrial cancer cell lines
2010-09-25 | E-TABM-992 | biostudies-arrayexpress
no omics defined Transcription profiling of human KNS42 cells treated with the dual pI3-kinas/mTOR inhibitor PI-103
2011-01-08 | E-TABM-890 | biostudies-arrayexpress
no omics defined Methylation and microRNA profiling of human paediatric glioma cell lines
2010-12-03 | E-TABM-858 | biostudies-arrayexpress
no omics defined Transcription profiling of human paediatric glioblastoma cells treated with insulin-like growth factor 1 receptor inhibitors
2011-01-08 | E-TABM-889 | biostudies-arrayexpress