Ontology highlight
ABSTRACT:
SUBMITTER: Walker ME
PROVIDER: S-EPMC10039758 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Walker Morgan E ME Simpson Joshua B JB Redinbo Matthew R MR
Current opinion in structural biology 20220713
Metagenomic sequencing data provide a rich resource from which to expand our understanding of differential protein functions involved in human health. Here, we outline a pipeline that combines microbial whole genome sequencing with protein structure data to yield a structural metagenomics-informed atlas of microbial enzyme families of interest. Visualizing metagenomics data through a structural lens facilitates downstream studies including targeted inhibition and probe-based proteomics to define ...[more]