Ontology highlight
ABSTRACT:
SUBMITTER: Chevalier G
PROVIDER: S-EPMC10046202 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Chevalier Guenson G Udovin Lucas L Otero-Losada Matilde M Bordet Sofia S Capani Francisco F Luo Sheng S Goetz Christopher G CG Perez-Lloret Santiago S
Brain sciences 20230317 3
The genetic basis of Neurogenic Orthostatic Hypotension (NOH) in Parkinson's disease (PD) has been inadequately explored. In a cross-sectional study, we examined the association between NOH and PD-related single-nucleotide polymorphisms (SNPs) and mapped their effects on gene expression and metabolic and signaling pathways. Patients with PD, free from pathological conditions associated with OH, and not taking OH-associated medications were included. NOH was defined as per international guideline ...[more]