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Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry.

ABSTRACT: Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, the available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, including plants, microorganisms, and marine creatures, have gained a lot of interest. Marine sources serve as reservoirs for new bioactive metabolites with various pharmacological activities. The marine-derived compound such as omega-3 acid ethyl esters, xyloketal B, asperlin, and saringosterol showed promising results in several CVDs. The present review focuses on marine-derived compounds' cardioprotective potential for hypertension, ischemic heart disease, myocardial infarction, and atherosclerosis. In addition to therapeutic alternatives, the current use of marine-derived components, the future trajectory, and restrictions are also reviewed.

SUBMITTER: Akram W

PROVIDER: S-EPMC10052127 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

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Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry.

Akram Wasim W Rihan Mohd M Ahmed Sakeel S Arora Swamita S Ahmad Sameer S Vashishth Rahul R

Marine drugs 20230321 3

Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, the available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, including plants, microorganisms, and marine creatures, have gained a lot of interest. Marine sources serve as reservoirs for new bioactive metabolites with various pharmacological activities. The marin ...[more]

PMID: 36976242

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