Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Gonzalez X
PROVIDER: S-EPMC10056055 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
García-González Xandra X Cubo Esther E Simón-Vicente Lucía L Mariscal Natividad N Alcaraz Raquel R Aguado Laura L Rivadeneyra-Posadas Jéssica J Sanz-Solas Antonio A Saiz-Rodríguez Miriam M
Journal of personalized medicine 20230222 3
Huntington's disease (HD) is an autosomal dominant progressive brain disorder, caused by a pathological expansion of a CAG repeat that encodes the huntingtin gene. This genetic neurodegenerative rare disease is characterized by cognitive, motor, and neuropsychiatric manifestations. The aim of the treatment is symptomatic and addresses the hyperkinetic disorders (chorea, dystonia, myoclonus, tics, etc.) and the behavioural and cognitive disturbances (depression, anxiety, psychosis, etc.) associat ...[more]