Ontology highlight
ABSTRACT:
SUBMITTER: Lee MF
PROVIDER: S-EPMC10056858 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Lee Michelle Felicia MF Wu Yuan Seng YS Poh Chit Laa CL
Viruses 20230308 3
Dengue is a major global health threat causing 390 million dengue infections and 25,000 deaths annually. The lack of efficacy of the licensed Dengvaxia vaccine and the absence of a clinically approved antiviral against dengue virus (DENV) drive the urgent demand for the development of novel anti-DENV therapeutics. Various antiviral agents have been developed and investigated for their anti-DENV activities. This review discusses the mechanisms of action employed by various antiviral agents agains ...[more]