Frequent first-trimester pregnancy loss in rhesus macaques infected with African-lineage Zika virus.
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ABSTRACT:
SUBMITTER: Rosinski JR
PROVIDER: S-EPMC10081769 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Publications
Frequent first-trimester pregnancy loss in rhesus macaques infected with African-lineage Zika virus.
Rosinski Jenna R JR Raasch Lauren E LE Barros Tiburcio Patrick P Breitbach Meghan E ME Shepherd Phoenix M PM Yamamoto Keisuke K Razo Elaina E Krabbe Nicholas P NP Bliss Mason I MI Richardson Alexander D AD Einwalter Morgan A MA Weiler Andrea M AM Sneed Emily L EL Fuchs Kerri B KB Zeng Xiankun X Noguchi Kevin K KK Morgan Terry K TK Alberts Alexandra J AJ Antony Kathleen M KM Kabakov Sabrina S Ausderau Karla K KK Bohm Ellie K EK Pritchard Julia C JC Spanton Rachel V RV Ver Hoove James N JN Kim Charlene B Y CBY Nork T Michael TM Katz Alex W AW Rasmussen Carol A CA Hartman Amy A Mejia Andres A Basu Puja P Simmons Heather A HA Eickhoff Jens C JC Friedrich Thomas C TC Aliota Matthew T MT Mohr Emma L EL Dudley Dawn M DM O'Connor David H DH Newman Christina M CM
PLoS pathogens 20230328 3
In the 2016 Zika virus (ZIKV) pandemic, a previously unrecognized risk of birth defects surfaced in babies whose mothers were infected with Asian-lineage ZIKV during pregnancy. Less is known about the impacts of gestational African-lineage ZIKV infections. Given high human immunodeficiency virus (HIV) burdens in regions where African-lineage ZIKV circulates, we evaluated whether pregnant rhesus macaques infected with simian immunodeficiency virus (SIV) have a higher risk of African-lineage ZIKV- ...[more]
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