Unknown

Dataset Information

0

Gestational weight gain in women with pre-pregnancy overweight or obesity and anthropometry of infants at birth.


ABSTRACT:

Objective

To examine the association of gestational weight gain (GWG) among women with pre-pregnancy overweight or obesity with infant weight and BMI z-score at birth.

Methods

This study is a secondary analysis of a randomized controlled trial including data from 208 infants at birth born by mothers with pre-pregnancy BMI between 28 and 45 kg/m2 who completed the APPROACH study (randomized to a high-protein low-glycemic index diet or a moderate-protein moderate-glycemic index diet). This analysis pooled the two diet treatment groups together and data were analyzed using a linear mixed model.

Results

Limiting GWG by 1 kg was associated with lower birthweight (-16 g, P = 0.003), BMI z-score (-0.03SD, P = 0.019), weight z-score (-0.03SD, P = 0.004), and infant abdominal circumference (-0.06 cm, P = 0.039). Infants born by mothers whose GWG was ≤9 kg weighed less (122 g, 95% CI: 6-249, P = 0.040), had similar BMI z-score (0.2SD, 95% CI: -0.06 to 0.55, P = 0.120), and lower incidence of emergency cesarean deliveries (11.5% vs. 23.1%, P = 0.044) compared to infants born by mothers whose GWG was >9 kg. When women were classified into GWG quartiles, women in Q1 (GWG range: -7.0 to 3.2 kg) gave birth to smaller infants (3,420 g, P = 0.015) with lower BMI z-score (-0.5SD, P = 0.041) than women in Q2 (3.3-7.1 kg), Q3 (7.2-10.9 kg) and Q4 (11.1-30.2 kg).

Conclusions

Limiting GWG among women with pre-pregnancy overweight or obesity was associated with lower infant weight, BMI z-score, weight z-score, and abdominal circumference at birth. Moreover, GWG below the Institute of Medicine guideline of a maximum of 9 kg was associated with lower birthweight and fewer emergency cesarean deliveries.

SUBMITTER: Mogensen CS 

PROVIDER: S-EPMC10084734 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

altmetric image

Publications

Gestational weight gain in women with pre-pregnancy overweight or obesity and anthropometry of infants at birth.

Mogensen Christina Sonne CS   Zingenberg Helle H   Svare Jens J   Astrup Arne A   Magkos Faidon F   Geiker Nina Rica Wium NRW  

Frontiers in pediatrics 20230316


<h4>Objective</h4>To examine the association of gestational weight gain (GWG) among women with pre-pregnancy overweight or obesity with infant weight and BMI z-score at birth.<h4>Methods</h4>This study is a secondary analysis of a randomized controlled trial including data from 208 infants at birth born by mothers with pre-pregnancy BMI between 28 and 45 kg/m<sup>2</sup> who completed the APPROACH study (randomized to a high-protein low-glycemic index diet or a moderate-protein moderate-glycemic  ...[more]

Similar Datasets

| S-EPMC4476720 | biostudies-literature
| S-EPMC7438242 | biostudies-literature
| S-EPMC6518700 | biostudies-literature
| S-EPMC10119439 | biostudies-literature
| S-EPMC5369251 | biostudies-literature
| S-EPMC4827014 | biostudies-other
| S-EPMC4865436 | biostudies-literature
| S-EPMC7355601 | biostudies-literature
| S-EPMC11481622 | biostudies-literature
| S-EPMC6345052 | biostudies-literature