Dataset Information

Time-varying association between cigarette and ENDS use on incident hypertension among US adults: a prospective longitudinal study.

ABSTRACT:

Objective

Electronic nicotine delivery systems (ENDS) products have emerged as the most popular alternative to combustible cigarettes. However, ENDS products contain potentially dangerous toxicants and chemical compounds, and little is known about their health effects. The aim of the present study was to examine the prospective association between cigarette and ENDS use on self-reported incident hypertension.

Design

Longitudinal cohort study.

Setting

Nationally representative sample of the civilian, non-institutionalised population in the USA.

Participants

17 539 adults aged 18 or older who participated at follow-up and had no self-reported heart condition or previous diagnosis of hypertension or high cholesterol at baseline.

Measures

We constructed a time-varying tobacco exposure, lagged by one wave, defined as no use, exclusive established use (every day or some days) of ENDS or cigarettes, and dual use. We controlled for demographics (age, sex, race/ethnicity and household income), clinical risk factors (family history of heart attack, obesity, diabetes and binge drinking) and smoking history (cigarette pack-years).

Outcomes

Self-reported incident hypertension diagnosis.

Results

The self-reported incidence of hypertension was 3.7% between wave 2 and wave 5. At baseline, 18.0% (n=5570) of respondents exclusively smoked cigarettes; 1.1% (n=336) exclusively used ENDS; and 1.7% (n=570) were dual users. In adjusted models, exclusive cigarette use was associated with an increased risk of self-reported incident hypertension compared with non-use (adjusted HR (aHR) 1.21, 95% CI 1.06 to 1.38), while exclusive ENDS use (aHR 1.00, 95% CI 0.68 to 1.47) and dual use (aHR 1.15, 95% CI 0.87 to 1.52) were not.

Conclusions

We found that smoking increased the risk of self-reported hypertension, but ENDS use did not. These results highlight the importance of using prospective longitudinal data to examine the health effects of ENDS use.

SUBMITTER: Cook S

PROVIDER: S-EPMC10124226 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Time-varying association between cigarette and ENDS use on incident hypertension among US adults: a prospective longitudinal study.

Cook Steven S Hirschtick Jana L JL Barnes Geoffrey G Arenberg Douglas D Bondarenko Irina I Patel Akash A Jiminez Mendoza Evelyn E Jeon Jihyoun J Levy David D Meza Rafael R Fleischer Nancy L NL

BMJ open 20230421 4

<h4>Objective</h4>Electronic nicotine delivery systems (ENDS) products have emerged as the most popular alternative to combustible cigarettes. However, ENDS products contain potentially dangerous toxicants and chemical compounds, and little is known about their health effects. The aim of the present study was to examine the prospective association between cigarette and ENDS use on self-reported incident hypertension.<h4>Design</h4>Longitudinal cohort study.<h4>Setting</h4>Nationally representati ...[more]

PMID: 37085311

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Dataset Information

Time-varying association between cigarette and ENDS use on incident hypertension among US adults: a prospective longitudinal study.

Objective

Design

Setting

Participants

Measures

Outcomes

Results

Conclusions

Publications

Time-varying association between cigarette and ENDS use on incident hypertension among US adults: a prospective longitudinal study.

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