Ontology highlight
ABSTRACT:
SUBMITTER: Grebstad Tune B
PROVIDER: S-EPMC10135607 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Grebstad Tune Benedicte B Melheim Maria M Åsegg-Atneosen Monica M Dotinga Baukje B Saugstad Ola Didrik OD Solberg Rønnaug R Baumbusch Lars Oliver LO
Biology 20230404 4
Birth asphyxia is the leading cause of death and disability in young children worldwide. Long non-coding RNAs (lncRNAs) may provide novel targets and intervention strategies due to their regulatory potential, as demonstrated in various diseases and conditions. We investigated cardinal lncRNAs involved in oxidative stress, hypoxia, apoptosis, and DNA damage using a piglet model of perinatal asphyxia. A total of 42 newborn piglets were randomized into 4 study arms: (1) hypoxia-normoxic reoxygenati ...[more]