Ontology highlight
ABSTRACT:
SUBMITTER: Dong Y
PROVIDER: S-EPMC10140337 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Dong Yue Y Zhang Kexin K Wei Jingge J Ding Yiyun Y Wang Xin X Hou Huiqin H Wu Jingyi J Liu Tianyu T Wang Bangmao B Cao Hailong H
Frontiers in immunology 20230414
Tumor immune microenvironment (TIME), a tumor-derived immune component, is proven to be closely related to the development, metastasis, and recurrence of tumors. Gut microbiota and its fermented-metabolites short-chain fatty acids (SCFAs) play a critical role in maintaining the immune homeostasis of gastrointestinal tumors. Consisting mainly of acetate, propionate, and butyrate, SCFAs can interact with G protein-coupled receptors 43 of T helper 1 cell or restrain histone deacetylases (HDACs) of ...[more]