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Thanksgiving to Yeast, the HMGB Proteins History from Yeast to Cancer.

ABSTRACT: Yeasts have been a part of human life since ancient times in the fermentation of many natural products used for food. In addition, in the 20th century, they became powerful tools to elucidate the functions of eukaryotic cells as soon as the techniques of molecular biology developed. Our molecular understandings of metabolism, cellular transport, DNA repair, gene expression and regulation, and the cell division cycle have all been obtained through biochemistry and genetic analysis using different yeasts. In this review, we summarize the role that yeasts have had in biological discoveries, the use of yeasts as biological tools, as well as past and on-going research projects on HMGB proteins along the way from yeast to cancer.

SUBMITTER: Lamas-Maceiras M

PROVIDER: S-EPMC10142021 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature

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Thanksgiving to Yeast, the HMGB Proteins History from Yeast to Cancer.

Lamas-Maceiras Mónica M Vizoso-Vázquez Ángel Á Barreiro-Alonso Aida A Cámara-Quílez María M Cerdán María Esperanza ME

Microorganisms 20230411 4

Yeasts have been a part of human life since ancient times in the fermentation of many natural products used for food. In addition, in the 20th century, they became powerful tools to elucidate the functions of eukaryotic cells as soon as the techniques of molecular biology developed. Our molecular understandings of metabolism, cellular transport, DNA repair, gene expression and regulation, and the cell division cycle have all been obtained through biochemistry and genetic analysis using different ...[more]

PMID: 37110415

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