Anti-HSP70 autoantibody formation by B-1 cells in Toxoplasma gondii-infected mice.
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ABSTRACT:
SUBMITTER: Chen M
PROVIDER: S-EPMC101692 | biostudies-literature | 2000 Sep
REPOSITORIES: biostudies-literature
Publications
Anti-HSP70 autoantibody formation by B-1 cells in Toxoplasma gondii-infected mice.
Chen M M Aosai F F Mun H S HS Norose K K Hata H H Yano A A
Infection and immunity 20000901 9
Formation of anti-Toxoplasma gondii HSP70 (TgHSP70) antibody cross-reactive to mouse HSP70 (mHSP70) was observed in the sera of BALB/c (a resistant strain) and C57BL/6 (B6; a susceptible strain) mice after peroral infection with T. gondii cysts of the Fukaya strain. The levels of anti-mHSP70 immunoglobulin G (IgG) autoantibody production in B6 mice were higher than those in BALB/c mice. The isotype and subclass of IgG of anti-TgHSP70 monoclonal antibodies cross-reactive to mHSP70 were mu and gam ...[more]
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