Ontology highlight
ABSTRACT:
SUBMITTER: Simon P
PROVIDER: S-EPMC10210203 | biostudies-literature | 2023 May
REPOSITORIES: biostudies-literature
ACS omega 20230511 20
The synthesis of kynurenic acid derivatives with potential biological effect was investigated and optimized for one-batch, two-step microwave-assisted reactions. Utilizing both chemically and biologically representative non-, methyl-, methoxy-, and chlorosubstituted aniline derivatives, in catalyst-free conditions, syntheses of seven kynurenic acid derivatives were achieved in a time frame of 2-3.5 h. In place of halogenated reaction media, tuneable green solvents were introduced for each analog ...[more]