Ontology highlight
ABSTRACT:
SUBMITTER: Chai R
PROVIDER: S-EPMC10213465 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Chai Rong R Li Ying Y Shui Linna L Ni Longxing L Zhang Ansheng A
Frontiers in cell and developmental biology 20230512
Programmed cell death has crucial roles in the physiological maturation of an organism, the maintenance of metabolism, and disease progression. Pyroptosis, a form of programmed cell death which has recently received much attention, is closely related to inflammation and occurs via canonical, non-canonical, caspase-3-dependent, and unclassified pathways. The pore-forming gasdermin proteins mediate pyroptosis by promoting cell lysis, contributing to the outflow of large amounts of inflammatory cyt ...[more]