Ontology highlight
ABSTRACT:
SUBMITTER: Sauve S
PROVIDER: S-EPMC10221096 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Sauve Stephanie S Williamson Joseph J Polasa Adithya A Moradi Mahmoud M
Membranes 20230425 5
The major facilitator superfamily (MFS) of transporters consists of three classes of membrane transporters: symporters, uniporters, and antiporters. Despite such diverse functions, MFS transporters are believed to undergo similar conformational changes within their distinct transport cycles, known as the rocker-switch mechanism. While the similarities between conformational changes are noteworthy, the differences are also important since they could potentially explain the distinct functions of s ...[more]