Ontology highlight
ABSTRACT:
SUBMITTER: Batishchev OV
PROVIDER: S-EPMC10226669 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Batishchev Oleg V OV Kalutskii Maksim A MA Varlamova Ekaterina A EA Konstantinova Anna N AN Makrinsky Kirill I KI Ermakov Yury A YA Meshkov Ivan N IN Sokolov Valerij S VS Gorbunova Yulia G YG
Frontiers in molecular biosciences 20230515
Porphyrins are well-known photosensitizers (PSs) for antibacterial photodynamic therapy (aPDT), which is still an underestimated antibiotic-free method to kill bacteria, viruses, and fungi. In the present work, we developed a comprehensive tool for predicting the structure and assessment of the photodynamic efficacy of PS molecules for their application in aPDT. We checked it on a series of water-soluble phosphorus(V) porphyrin molecules with OH or ethoxy axial ligands and phenyl/pyridyl periphe ...[more]