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Shortwave infrared fluorescence imaging of peripheral organs in awake and freely moving mice.

ABSTRACT: Extracting biological information from awake and unrestrained mice is imperative to in vivo basic and pre-clinical research. Accordingly, imaging methods which preclude invasiveness, anesthesia, and/or physical restraint enable more physiologically relevant biological data extraction by eliminating these extrinsic confounders. In this article, we discuss the recent development of shortwave infrared (SWIR) fluorescent imaging to visualize peripheral organs in freely-behaving mice, as well as propose potential applications of this imaging modality in the neurosciences.

SUBMITTER: Arus BA

PROVIDER: S-EPMC10232761 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Shortwave infrared fluorescence imaging of peripheral organs in awake and freely moving mice.

Arús Bernardo A BA Cosco Emily D ED Yiu Joycelyn J Balba Ilaria I Bischof Thomas S TS Sletten Ellen M EM Bruns Oliver T OT

Frontiers in neuroscience 20230518

Extracting biological information from awake and unrestrained mice is imperative to <i>in vivo</i> basic and pre-clinical research. Accordingly, imaging methods which preclude invasiveness, anesthesia, and/or physical restraint enable more physiologically relevant biological data extraction by eliminating these extrinsic confounders. In this article, we discuss the recent development of shortwave infrared (SWIR) fluorescent imaging to visualize peripheral organs in freely-behaving mice, as well ...[more]

PMID: 37274204

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