Ontology highlight
ABSTRACT:
SUBMITTER: Bryan NW
PROVIDER: S-EPMC10245869 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Bryan Nikaela W NW Ali Aamir A Niedzialkowska Ewa E Mayne Leland L Stukenberg P Todd PT Black Ben E BE
bioRxiv : the preprint server for biology 20230723
The physical basis of phase separation is thought to consist of the same types of bonds that specify conventional macromolecular interactions yet is unsatisfyingly often referred to as 'fuzzy'. Gaining clarity on the biogenesis of membraneless cellular compartments is one of the most demanding challenges in biology. Here, we focus on the chromosome passenger complex (CPC), that forms a chromatin body that regulates chromosome segregation in mitosis. Within the three regulatory subunits of the CP ...[more]