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Geminal Charge-Assisted Tetrel Bonds in Bis-Pyridinium Methylene Salts.

ABSTRACT: C(sp³) atoms are known to act as electrophilic sites in self-assembly processes, and in all cases reported till now, they form only one interaction with nucleophiles; that is, they function as monodentate tetrel bond donors. This manuscript reports experimental (X-ray structural analysis) and theoretical evidence (DFT calculations), proving that the methylene carbon in bis-pyridinium methylene salts establishes two short and directional C(sp³)···anion interactions; that is, they function as bidentate tetrel bond donors.

SUBMITTER: Calabrese M

PROVIDER: S-EPMC10324100 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

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Geminal Charge-Assisted Tetrel Bonds in Bis-Pyridinium Methylene Salts.

Calabrese Miriam M Pizzi Andrea A Daolio Andrea A Ursini Maurizio M Frontera Antonio A Demitri Nicola N Lenczyk Carsten C Wojciechowski Jakub J Resnati Giuseppe G

Crystal growth & design 20230214 3

C(sp<sup>3</sup>) atoms are known to act as electrophilic sites in self-assembly processes, and in all cases reported till now, they form only one interaction with nucleophiles; that is, they function as monodentate tetrel bond donors. This manuscript reports experimental (X-ray structural analysis) and theoretical evidence (DFT calculations), proving that the methylene carbon in bis-pyridinium methylene salts establishes two short and directional C(sp<sup>3</sup>)···anion interactions; that is, ...[more]

PMID: 37426903

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