Ontology highlight
ABSTRACT:
SUBMITTER: Carreira LAM
PROVIDER: S-EPMC10329633 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Carreira Luís António Menezes LAM Szadkowski Dobromir D Lometto Stefano S Hochberg Georg K A GKA Søgaard-Andersen Lotte L
Nature communications 20230708 1
During cell migration, front-rear polarity is spatiotemporally regulated; however, the underlying design of regulatory interactions varies. In rod-shaped Myxococcus xanthus cells, a spatial toggle switch dynamically regulates front-rear polarity. The polarity module establishes front-rear polarity by guaranteeing front pole-localization of the small GTPase MglA. Conversely, the Frz chemosensory system, by acting on the polarity module, causes polarity inversions. MglA localization depends on the ...[more]