TSC22D3 as an immune-related prognostic biomarker for acute myeloid leukemia.
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ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC10415931 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Publications
TSC22D3 as an immune-related prognostic biomarker for acute myeloid leukemia.
Li Yang Y Huang Hanying H Zhu Ziang Z Chen Shuzhao S Liang Yang Y Shu Lingling L
iScience 20230722 8
Acute myeloid leukemia (AML) is the type of hematologic neoplasm most common in adults. Glucocorticoid-induced gene <i>TSC22D3</i> regulates cell proliferation through its function as a transcription factor. However, there is no consensus on the prognostic and immunoregulatory significance of <i>TSC22D3</i> in AML. In the present study, we evaluated the correlation between <i>TSC22D3</i> expression, immunoinfiltration, and prognostic significance in AML. Knockdown of <i>TSC22D3</i> significantly ...[more]
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