Ontology highlight
ABSTRACT:
SUBMITTER: Smith CA
PROVIDER: S-EPMC104536 | biostudies-literature | 1998 May
REPOSITORIES: biostudies-literature
Smith C A CA Driscoll D A DA Emanuel B S BS McDonald-McGinn D M DM Zackai E H EH Sullivan K E KE
Clinical and diagnostic laboratory immunology 19980501 3
We wished to determine the prevalence of immunoglobulin A (IgA) deficiency in patients with the chromosome 22q11.2 deletion syndrome. A total of 32 patients with the chromosome 22q11.2 deletion were examined for IgA deficiency. We report a 13% (n = 4) prevalence of IgA deficiency in patients with this syndrome. The odds ratio of IgA deficiency in this population is 14.20 (P < 0.0001). This confirms the occurrence of significant humoral deficits in this predominantly cellular immunodeficiency. ...[more]