Ontology highlight
ABSTRACT:
SUBMITTER: Moreira J
PROVIDER: S-EPMC10465969 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Moreira João J Machado Mariana M Dias-Teixeira Mónica M Ferraz Ricardo R Delerue-Matos Cristina C Grosso Clara C
Acta pharmaceutica Sinica. B 20230620 8
Neurodegenerative and neuropsychiatric diseases are increasingly affecting individuals' quality of life, thus increasing their cost to social and health systems. These diseases have overlapping mechanisms, such as oxidative stress, protein aggregation, neuroinflammation, neurotransmission impairment, mitochondrial dysfunction, and excitotoxicity. Currently, there is no cure for neurodegenerative diseases, and the available therapies have adverse effects and low efficacy. For neuropsychiatric dis ...[more]