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ABSTRACT: Background
The outbreak of the coronavirus disease 2019 (COVID-19) has become an evolving worldwide health crisis. With the rising prevalence of diabetes mellitus has come an increasing awareness of their impacts on infectious diseases, and the risk for postinfection complications and mortality from critical infections.Objective
The objective of this study was to evaluate the prevalence and impact of diabetes mellitus on the severity and mortality of COVID-19.Methods
Data of laboratory-confirmed hospitalized patients at the COVID-19 unit between September 2020 and August 2021 were analyzed, in a cross-sectional study. The population was classified into two groups: COVID-19 patients with and without diabetes. Primary outcomes were the overall length of hospital stay, the admission to the ICU, and death. The association between diabetes and death was assessed in a Cox proportional hazards model.Results
A total of 866 patients were included. There were 270 (31.2%) patients with diabetes. Diabetic patients were more likely to have hypertension (58.1 vs. 33.4%), cardiovascular disease (18.5 vs. 10.4%), and dyslipidaemia (17.8 vs. 7.2). Overall, 263 patients died, among them only 86 in the diabetic group (P=0.523). Patients with diabetes had a higher risk of developing complications (P<0.001). Multivariate Cox regression analysis showed that diabetes was not significantly associated with death [HR (95% CI): 1.253 (0.963-1.631)].Conclusion
Diabetes was associated with a greater risk of complications in patients with COVID-19. Special attention to diabetic patients during treatment must be given to avoid these complications.
SUBMITTER: Rouis S
PROVIDER: S-EPMC10473318 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Rouis Sana S Chebil Dhekra D Debbabi Wided W Hannachi Hajer H Sakly Hela H Chermiti Sondes S Marzouk Hajer H Kharrat Issam I Samet Slim S Merzougui Latifa L
Annals of medicine and surgery (2012) 20230801 9
<h4>Background</h4>The outbreak of the coronavirus disease 2019 (COVID-19) has become an evolving worldwide health crisis. With the rising prevalence of diabetes mellitus has come an increasing awareness of their impacts on infectious diseases, and the risk for postinfection complications and mortality from critical infections.<h4>Objective</h4>The objective of this study was to evaluate the prevalence and impact of diabetes mellitus on the severity and mortality of COVID-19.<h4>Methods</h4>Data ...[more]