Ontology highlight
ABSTRACT:
SUBMITTER: Pleiko K
PROVIDER: S-EPMC10481362 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Pleiko Karlis K Haugas Maarja M Parfejevs Vadims V Pantelejevs Teodors T Parisini Emilio E Teesalu Tambet T Riekstina Una U
Molecular therapy. Nucleic acids 20230816
Targeted therapies have increased the treatment options for triple-negative breast cancer patients. However, the paucity of targetable biomarkers and tumor heterogeneity have limited the ability of precision-guided interventions to live up to their full potential. As affinity-targeting ligands, aptamers show high selectivity toward target molecules. Compared with antibodies, aptamers have lower molecular weight, increased stability during transportation, reduced immunogenicity, and increased tis ...[more]