Ontology highlight
ABSTRACT:
SUBMITTER: Torres AY
PROVIDER: S-EPMC10518265 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
Torres Alba Yurani AY Nano Maddalena M Campanale Joseph P JP Deak Sierra S Montell Denise J DJ
The Journal of cell biology 20230925 11
Src family kinases (SFKs) are evolutionarily conserved proteins acting downstream of receptors and regulating cellular processes including proliferation, adhesion, and migration. Elevated SFK expression and activity correlate with progression of a variety of cancers. Here, using the Drosophila melanogaster border cells as a model, we report that localized activation of a Src kinase promotes an unusual behavior: engulfment of one cell by another. By modulating Src expression and activity in the b ...[more]